Eating just two cups of mango a day can help lower insulin concentrations and improve insulin sensitivity in overweight or obese adults with chronic low-grade inflammation, according to new research.

The study, conducted at the Illinois Institute of Technology and published in Nutrients, brings a sweet and antioxidant-rich way for individuals to reduce their risk of chronic conditions, such as type 2 diabetes, in under roughly 100 calories. 

The study compared the consumption of fresh mangos to calorie-matched Italian ices in 48 adults aged 20-60, examining their effects on inflammation and insulin sensitivity in overweight and obese adults with low-grade chronic inflammation.

Those who ate mangoes saw a significant reduction in insulin resistance and improved blood sugar levels, and after four weeks, experienced significantly lower insulin concentrations compared to the beginning of the study. Those in the mango grouping also saw stable body composition, while the control group saw a “slight but significant increase in body weight,” researchers noted.

“Managing blood glucose isn’t just about monitoring blood sugar levels—it’s about improving insulin sensitivity,” noted Indika Edirisinghe, PhD, Professor of Food Science and Nutrition. “Our study suggests that adding fresh mangos to the diet can be a simple, enjoyable way for people who are overweight or have obesity to support better insulin function and reduce type 2 diabetes risk.”

Additional findings showed that inflammation markers and glucose levels weren’t significantly different between the two groups, deeming mangos a “heart-healthy swap for calorically comparable sweet treats.” No differences were noted in terms of fasting total cholesterol, LDL cholesterol, HDL cholesterol or triglycerides, according to the study.

“The improvement in insulin sensitivity in the mango group, without changes in body weight, is noteworthy – which counters misconceptions about mangos’ natural sugar content and impact on obesity and diabetes,” Edirisinghe added.  “These findings support previous research showing that eating mango does not lead to weight gain, and while the exact mechanism is still unknown, the role of improved antioxidant status from mango consumption may be the mediating factor on blood glucose control.”

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It’s included in every fitness certification exam prep: mitochondria, and for good reason.

Mitochondrial DNA (mtDNA) plays a vital role in cellular energy production, and its stability is crucial for overall cell function. However, disruptions in the balance between mtDNA transcription and replication can lead to various diseases and contribute to the aging process.

A new study led by researchers in Japan has uncovered the role of mitochondrial transcription elongation factor (TEFM) in regulating this balance, offering potential insights for therapeutic advancements. For fitness professionals, understanding mitochondrial function at a deeper level can inform training strategies aimed at optimizing energy production, recovery and overall cellular health.

Published in Communications Biology on February 8, the researchers findings provide a deeper understanding of how mtDNA transcription and replication processes interact, which could have significant implications for health and disease management.

The Importance of mtDNA Regulation

Mitochondria serve as the powerhouse of the cell, generating energy through oxidative phosphorylation, a process that relies on the proper functioning of mtDNA. Unlike nuclear DNA, mtDNA is more vulnerable to mutations and instability, making its maintenance a critical area of study. Previous research has indicated that an imbalance in mtDNA transcription and replication can lead to mitochondrial dysfunction, a hallmark of numerous diseases and aging-related decline.

To investigate how TEFM influences mtDNA maintenance, the research team utilized genome editing techniques to create human cell cultures with TEFM knocked out. The study revealed that TEFM deficiency led to a significant reduction in mtDNA copy number, a decline in 7S DNA levels, and impaired strand-asynchronous replication intermediates — key indicators of mtDNA replication efficiency.

These findings suggest that TEFM plays a crucial role in regulating mtDNA replication, particularly at the heavy-strand origin of replication.

Interestingly, the absence of TEFM also triggered an increase in transcription initiation from the light-strand promoter, as evidenced by elevated levels of mitochondrial transfer RNA (tRNA Pro). However, despite this surge in transcription, the replication intermediates remained significantly reduced, indicating that TEFM is essential for maintaining the balance between these two processes.

Another significant discovery from the study was TEFM’s interaction with DNA polymerase γ (POLG), the primary enzyme responsible for mtDNA replication. This interaction suggests that TEFM not only facilitates transcription elongation but also has a direct impact on replication processes. Understanding this relationship could be key to future therapeutic strategies aimed at mitigating mtDNA-related disorders, such as mitochondrial myopathies, Leigh syndrome, MELAS syndrome, and Leber’s hereditary optic neuropathy.

Implications and Future Research

The study’s findings mark a significant advancement in mitochondrial biology, but many questions remain unanswered. Future research will aim to pinpoint the exact locations of TEFM and POLG interactions on mtDNA and further clarify their role in the overall replication mechanism.

“Our study addresses a fundamental question in mitochondrial gene expression regulation,” said Dr. Takehiro Yasukawa, associate professor at Juntendo University. “By deepening our understanding of TEFM’s role in maintaining transcription-replication balance, we hope to pave the way for new treatments targeting mtDNA-related diseases.”

Given the increasing interest in mitochondrial health within the fitness and wellness industries, this research could have long-term implications for strategies aimed at improving cellular function, longevity and disease prevention. As the scientific community continues to uncover the complexities of mtDNA regulation, the fitness and health sectors may soon benefit from these breakthroughs in ways that extend beyond traditional medical applications.

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Halotherapy Solutions has spent years advancing the role of halotherapy in recovery, earning recognition from gyms, wellness centers and now, even Prince Harry. As the only BBB-accredited salt therapy equipment company with an A+ rating, the company is known for its commitment to quality and customer support.

“Our company strongly believes that giving back is core to being a business,” says Steve Spiro, CEO of Halotherapy Solutions.

At the 2025 Vancouver Invictus Games, Halotherapy Solutions shared HaloRed, a patented recovery technology that combines Halotherapy with advanced red light therapy, to paralympic military athletes from 23 countries. Designed to enhance respiratory function, accelerate muscle recovery and reduce inflammation, HaloRed quickly gained attention for its science-backed benefits. 

The response was overwhelming, with athletes and wellness practitioners praising its impact — leading to an invitation to the 2027 Invictus Games in the UK and the U.S. Armed Forces Warrior Games in Colorado.

Halotherapy Solutions is helping fitness and wellness businesses integrate recovery solutions that support both health and performance. The following Q&A with Spiro dives into the brand’s experience at the Invictus Games, meeting with Prince Harry, and why halotherapy is becoming a key part of athletic recovery.

Athletech News (ATN): Halotherapy Solutions was part of the 2025 Vancouver Invictus Games, where you met Prince Harry. Can you tell us about that experience?

Steve Spiro (SS): Meeting Prince Harry was an incredible moment. His passion for wellness, recovery and holistic health was evident, and he was genuinely interested in the benefits of Halotherapy for athletes. The Healing Hut, where we were featured, included 25 world-renowned wellness practitioners, from massage therapists and acupuncturists to aromatherapists and physical therapists — and even Mattis, the loving service dog!

Halotherapy Solutions was one of just two wellness equipment providers handpicked for this global event, and it was incredible to be part of a space that focused on helping military athletes recover and perform at their best.

ATN: How did athletes and attendees respond to your Halotherapy sessions?

SS: The response was overwhelming! We provided over 1,000 free salt therapy sessions to more than 1,400 paralympic military athletes and their families from 23 countries — plus some generals, CEOs and wellness leaders. Many athletes said our HaloRed system helped alleviate colds, reduced stress and improved lung function for training and recovery.

ATN: What makes Halotherapy such a powerful tool for athletes?

SS: Breath is the foundation of performance. Whether an athlete is competing at the highest level or just training for personal goals, respiratory function directly impacts endurance, recovery and overall health. Halotherapy works by clearing airways to improve oxygen intake and stamina, reducing inflammation for faster muscle recovery, lowering stress levels to aid focus and performance and more.

Athletes recognize the power of recovery, and halotherapy is an accessible, non-invasive solution that enhances both physical and mental resilience.

ATN: Why should gyms, recovery centers and wellness businesses consider adding Halotherapy?

SS: Wellness is no longer a niche offering — it’s a core expectation in the fitness and wellness industry. Gyms are seeing that integrating recovery solutions like Halotherapy drives new membership, boosts retention and increases revenue per member.

The HaloRed system has become our top-selling product in the fitness industry because it fits seamlessly into recovery programs and performance optimization strategies. We’ve already partnered with Equinox, World Gym, and Augment, along with several pro sports teams and independent fitness centers that recognize the value of better respiratory stamina, faster recovery and holistic wellness.

ATN: What makes HaloRed different from other halotherapy solutions?

SS: HaloRed is the only patented system that combines salt therapy with red light therapy, and it’s backed by science. We worked with NASA to study how salt crystals refract red light, creating microbursts of energy that enhance its effects. This makes our red light therapy more immersive and effective than standard medical-grade red light therapy, which typically only offers two wavelengths — we use four.

Additionally, our HaloCBD technology allows facilities to offer Aerobic CannaBinoiD Therapy, where CBD is combined with salt and dispersed through our halogenerators, providing benefits like reduced inflammation, improved sleep and better breathing — without requiring users to consume it through smoke or a vape.

ATN: How does Prince Harry’s involvement in wellness impact the future of recovery solutions like Halotherapy?

SS: Prince Harry has been a strong advocate for mental and physical well-being, particularly for military personnel and athletes (editor’s note: Prince Harry founded the Invictus Games in 2014). His continued support of events like the Invictus Games and commitment to holistic wellness practices helps drive awareness and credibility for recovery solutions that work.

The fact that world-class athletes, high-ranking officials and leaders in wellness experienced Halotherapy Solutions firsthand at the Invictus Games reinforces that this is more than just a trend — it’s the future of athletic recovery.

ATN: Where can fitness and wellness businesses learn more about integrating Halotherapy into their facilities?

SS: We’d love to connect! Visit us at Booth #869 at HFA for a live demo or reach out to explore how Halotherapy Solutions can help your business grow with next-generation recovery technology.

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Life Time has opened its 14th luxury athletic country club in Illinois — the first of 2025 — and its second location to feature the Miora Performance and Longevity Clinic, where Life Time members can access personalized health guidance, personal trainers, recovery and longevity therapies and weight loss medications.

The news follows another strong quarter, where Life Time reported an 18.7% increase in revenue to $663.3 million for Q4 2024 and an 18.2% increase to $2.62 billion for the full year.

The 60,000-square-foot Life Time destination is located in the downtown Evanston area and features three indoor pickleball courts, Life Time’s signature recovery zone with Dynamic Stretch, hydromassage beds, cryotherapy beds and Normatec devices, personal and group training programs, five dedicated studios for 90+ weekly group classes, state-of-the-art fitness equipment, a Kids Academy, a LifeCafe smoothie and coffee bar and a dedicated Life Time Work Club Lounge space.

“Life Time Evanston is the first of many planned 2025 openings and also marks the expansion of our Miora performance and longevity clinic beyond Minnesota, allowing even more people to experience the multidimensional approach we’re taking to address all aspects of health and wellness,” said Parham Javaheri, Life Time executive vice president, president club operations and chief of property development officer. “We’re excited to extend our unparalleled Life Time experience to Evanston in a prime location that will serve this community and bring renewed energy to the downtown area.”

Former Life Time chief operating officer and president Jeff Zwiefel told Athletech News late last year that the Miora concept was created to democratize access to health-optimization services.  

“The consumer, now more than ever, is interested in optimal health; they’re interested in looking good, feeling great, and living longer, better,” Zwiefel said. “And there wasn’t a viable, trusted solution on a national basis (that was) out there. … We felt like we could be a tremendous one-stop-shop solution for our customers.”

Miora members start with a blood test that measures more than 90 biomarkers, providing data that guides a personalized blend of longevity, weight loss and performance protocols. The first Miora launched in Life Time’s flagship Target Center club in Minneapolis, Minnesota, as a pilot program.

“We’re now at the stage where we are planning to roll out hub-and-spoke destinations across the other 180-plus lifetime locations,” Zwiefel confirmed. “We’re going to continue to thoughtfully roll Miora out in a very pragmatic and impactful way, but making sure that we continue to maintain the right quality as we scale – and consistency.”

While Miora is poised to be a hit with Life Time members, the athletic country club operator is also breaking new ground with its free LT Digital app, which CEO Bahram Akradi says has attracted more than 1.7 million non-member subscribers, all without any marketing efforts. The number is expected to reach three to four million by the end of the year, he told investors last week.

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Naboso, a sensory tech company with a line that includes textured insoles, socks, mats, flooring and release tools, has partnered with Chi Living, the parent brand of ChiRunning and ChiWalking.

The partnership between the two kicks off at the Boston Run Show on March 1-2 at the Boston Convention Center. The two plan to launch a series of educational initiatives, workshops and product integrations.

“We are thrilled to join forces with Chi Living to bring an integrated approach to movement and wellness,” said Dr. Emily Splichal, Nabosco founder, functional podiatrist and human movement specialist. “This partnership allows us to further our mission of enhancing mobility and longevity by supporting the body from the ground up.”

Chi Living founder Danny Dreyer noted that the two entities are committed to helping people move easily and efficiently. Along with offering a holistic movement technique, Chi Living has evolved into a platform with a teaching component for aspiring instructors and coaches, along with apps for both running and walking.

“Naboso’s sensory-stimulating products offer greater benefits to individuals looking to optimize their movement for a lifetime,” Dreyer added.

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Biograph, the San Francisco Bay Area’s preventive health and diagnostic clinic co-founded by Dr. Peter Attia, is preparing to open a second location in New York City this quarter.

The preventative health and longevity concept currently offers two membership levels: Core, $7,500, which provides a “point-in-time” assessment of health, and Black, a $15,000 option offering more comprehensive health insights via 30+ assessments and ongoing expert guidance. Depending on the selected level, members will have their risk assessed across several categories including cancer, metabolic, cardiac, neurological and quality of life.

“Diagnostics are foundational to evaluating and implementing an effective health strategy informed by a systems-based approach, as well as comprehensive analyses that consider each data point within the context of an individual’s entire health picture,” Attia said. “Biograph’s evaluation is best in class, which is why I recommend my patients start here.”

According to Biograph, since the launch of its first clinic, more than 15% of members have reported discovering urgent or life-altering health insights. To that point, co-founder John Hering noted that Biograph was inspired by the cancer diagnosis of one of his best friends.

“Biograph was founded on the belief that with the proper application of advanced medical technology and early detection, we can save lives,” Hering explained. “There is no greater investment we can make in the future, as individuals or humanity, than in our health. With an approach rooted in scientific evidence, Biograph is poised to be an integral catalyst helping to redefine what it means to live a better and longer life.”

The clinic touts a concierge setting supported by a team of medical experts, including Dr. Michael Doney, who is credited with refining Biograph’s assessment protocol and serves as executive medical director. Once an emergency medicine physician, Dr. Doney has pivoted to precision longevity care and research.

“Recognizing the variability in quality among health tests, scans, and assessments, I was drawn to Biograph’s mission,” Doney said. “We are committed to providing the most in-depth analysis of a broad range of health factors, enabling members to not only extend their lifespan but, more importantly, to optimize their healthspan and overall quality of life.”

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For too long, menopause has been treated as a taboo topic. Maria Luque, PhD, hopes to change the conversation around the transition. A health science professor, fitness expert and menopause specialist, Luque is on a mission to empower women with the knowledge and tools they need to navigate menopause with confidence.

Luque serves as Halle Berry’s menopause coach, guiding the Oscar-winning actress through her personal journey as part of Respin Health, the just-launched wellness initiative Berry co-founded. Her expertise in menopause and fitness is built on decades of research and hands-on experience.

“My background as a health science professor means I’ve always been committed to science-backed strategies, ensuring that everything I teach is rooted in evidence,” she explained. “But science alone isn’t enough—real change happens when knowledge meets practical, individualized application. That’s where my 20 years of coaching experience come in.”

She has spent years guiding women through the challenges of menopause, helping them understand their bodies and build effective habits.

“This dual perspective—bridging research with real-world coaching—defines my approach,” she said. “It’s not about generic advice; it’s about creating personalized strategies that empower women to thrive.”

When Halle Berry set out to experience the Respin Health pilot program, she wanted to do so as a participant.

“She understands the power of coaching and community,” Luque shared. “She wanted to go through the process herself to fully embrace what we’re building. With my extensive experience and personalized approach, she chose me as her coach to guide her through this journey. It’s been an incredible collaboration because she’s deeply committed to sharing real, science-backed solutions for menopause. She embodies the message that every woman deserves this level of support.”

A cornerstone of Luque’s menopause coaching is strength training, which she insists is critical for women going through perimenopause and menopause.

“Resistance training is non-negotiable for women in perimenopause and menopause,” she stated. “It’s not just a fitness trend—it’s backed by decades of science showing its critical role in preserving muscle, metabolism and bone density, as well as improving cognitive function and mental well-being.”

Declining estrogen levels during menopause contribute to muscle loss, which in turn affects metabolism, increases fat storage and weakens bones.

“Strength training is the most effective way to counteract these changes and maintain long-term vitality,” she said. “But the benefits go beyond just the physical. Strength training has a profound impact on mental health and body image. Instead of focusing on what’s being ‘lost,’ strength training shifts the perspective to what’s being gained—strength, capability, confidence and a renewed sense of control over one’s body. Studies also show that resistance training reduces anxiety, depression and stress, making it a key tool for overall well-being.”

Luque emphasized that there’s no one-size-fits-all approach and that menopause care has been fragmented for too long, often leaving women to navigate the transition on their own. Respin Health is working to change that by offering proactive, personalized coaching.

“For too long, menopause support has been reactive—women are left to figure it out themselves or rely on outdated, one-size-fits-all advice,” she said. “At Respin Health, we’re changing that by providing science-backed, personalized coaching that is proactive, precise and deeply personal.”

One of the biggest gaps Luque and Respin Health aim to fill is empowerment.

“We don’t just offer guidance—we give women the tools, education and support to become their own best advocates,” she says. “Instead of passive, single-dimensional care, we create tailored solutions that help women understand their bodies, make informed choices and take control of their health.”

Another key differentiator is community.

“Menopause can feel isolating, but it doesn’t have to be,” Luque stated. “Women thrive when they have a supportive space to share experiences, ask questions and learn from one another. Our coaching model brings women together so they can feel heard, validated and empowered.”

Luque’s message is clear: menopause isn’t something to fear—it’s a new chapter and with the right tools, it can be a strong one.

“At the core of my coaching is this simple truth: movement should feel like a gift, not a punishment,” she said. “When we make that shift, everything else—consistency, strength, confidence—falls into place.”

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The hospitality industry is undergoing a fundamental shift as longevity and wellness take center stage in consumer preferences. From biohacking and personalized health programs to recovery-focused fitness amenities and medical-grade wellness treatments, hotels and resorts are expanding their offerings to meet the growing demand for longevity-focused experiences.

Several key factors are fueling this transformation. First, the global wellness economy was valued at $5.6 trillion in 2022, with wellness tourism projected to reach $1 trillion by the end of this year. Travelers today are prioritizing proactive health measures, pushing hotels beyond traditional spa services to incorporate longevity-driven experiences, including IV therapy, full-body diagnostics and performance recovery tools.

At the same time, the aging global population is reshaping travel habits. In the United States alone, the percentage of individuals aged 65 and older has doubled from 8% in 1950 to 16.9% in 2020. Consumers over 50 — collectively known as the Longevity Economy – contributed $45 trillion to the global GDP in 2020, highlighting their significant spending power.

Further, this travel is not limited to seniors. Younger generations are increasingly integrating trends such as biohacking, cryotherapy and hyper-personalized nutrition into their lifestyles and seeking it on the road.

All told, this presents an enormous opportunity for hospitality brands to cater to a new era of travelers. Recognizing this shift, FIBO is launching its first-ever Longevity and Hospitality Summit as part of its annual conference in April.

Athletech News spoke with Judith Cartwright, a leading expert in this space and a key speaker at the summit, to explore how hotels and resorts can successfully integrate longevity into their offerings.

The Need for a Strategic Approach

“Longevity is not just a trend, it is here to stay, and hoteliers and developers need to have a strategic plan for how this gets incorporated,” says Cartwright.

This integration, she explains, needs to go beyond guest services and begin internally. 

“This starts with the hardware of a hotel and continues throughout the offering — not only for the guests but also for employees, creating awareness and solutions for their day-to-day workplace environment.”

Despite growing demand, many hotels and resorts still struggle with the positioning of wellness and fitness services.

“The challenge hotels and resorts across all star ratings have is that often their gyms, spas and wellness facilities are not seen as profit centers,” Cartwright explains. “They are treated as amenities rather than business units, leading to missed opportunities. Additionally, often the head of wellness and fitness is brought in just weeks before opening, rather than being involved from the start to help shape offerings.”

Another major issue is outdated brand standards.

“For example, the standard of a 60-square-meter gym for every 100 hotel rooms is simply not sufficient anymore,” she says. “Again, getting the right experts involved early in the architectural design phase allows hotels to create facilities that set them apart from competitors.”

Moving Beyond the Spa Model

Cartwright emphasizes that hotels must move past traditional concepts and recognize how wellness has evolved.

“The biggest hurdle is understanding that wellness has transformed beyond spas and fitness centers. Cost versus profitability is a major factor, but developing a concept that integrates wellness fundamentally throughout design, operations, marketing, customer service and the guest experience is the necessary approach. It’s about storytelling and ‘story-doing’ and educating the team beyond the wellness department before guests even arrive.”

She notes that there are significant opportunities in making this shift. “Industry leaders can move beyond the traditional spa model and incorporate a 360-degree approach. Understanding the customer base, identifying what guests are looking for and building financial models around those needs is key.”

The end goal is to meet consumer expectations for a longer, healthier life —  even when traveling.

“Sleep and nutrition are two of the most overlooked aspects of hotel wellness,” Cartwright says. “Hotels invest in pillow menus and room scents, yet guests still deal with bright alarm clocks, blinking fire detectors, and poorly designed blackout curtains. And children’s menus? They’re still full of pizza, pasta and chicken nuggets instead of balanced, nutritious options.”

The Opportunity for Hospitality Brands

Hotels and resorts have a major opportunity to develop and offer meaningful longevity-focused services.

“The investment can be made at any scale,” Cartwright explains. “It depends on your customer base. Don’t create something just because it’s trendy —  understand what your guests are looking for and develop from there. Thorough benchmarking and gap analysis are crucial.”

According to Cartwright, several brands are already excelling in this space. “Equinox, SIRO, Lanserhof, Chenot, Clinique La Prairie and SHA Wellness Clinic are all approaching longevity in different ways, but they share a common focus: providing guests with meaningful, transformative experiences that go beyond standard hospitality.”

As longevity continues to shape the future of travel, hotels and resorts must position themselves at the forefront of this movement. It’s no longer just about offering a luxurious stay —  it’s about providing a transformative experience that enhances health, well-being and longevity.

For those looking to stay ahead of this movement, FIBO’s Longevity and Hospitality Summit will bring together thought leaders, industry pioneers and hospitality executives to explore the opportunities ahead. With expert insights, innovative solutions and actionable strategies, this event is set to redefine the future of wellness-driven hospitality.

Learn more about the summit and register today.

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Onvy HealthTech Group has secured more than $2 million in a seed extension financing round that will fuel the expansion of its AI-based health coaching platform. 

Voloridge Health, LLC led the round. 

The Munich-based Onvy is in the business of precision wellness with its AI Health Coach app that integrates more than 320 wearables, environmental data, health sensors and behavioral data to make health recommendations and provide instant feedback on important metrics.

Last year, the startup was recognized by Statista and Newsweek as one of the world’s best digital health companies of 2024. 

Onvy founder and CEO Adrian Kochsiek is personally invested in advancing human health prevention, sharing on LinkedIn that he’s a cancer survivor and that his experience was the driving force in creating proactive solutions, beginning with his first startup, MitoCare. 

In one post on the career networking site, he noted that DNA doesn’t equate to destiny, writing, “your genes load the gun, your lifestyle pulls the trigger” – a notable phrase, as new research indicates that a range of environmental factors have a greater influence than genetics when it comes to aging and premature mortality.

“The future of health is real-time, hyper-personalized and AI-driven,” Kochsiek said. “Yet, the industry still relies on outdated, delayed and one-size-fits-all approaches. At Onvy, we are changing that. Our platform transforms raw health data into instant, tailored guidance—empowering users to take action when it matters most. With this investment, we are scaling AI-driven precision health to revolutionize how individuals and businesses engage with well-being.”

The new capital will also advance Onvy’s B2B endeavors in the “AI Health Coach-as-a-Service” realm and respond to rising demand, where corporate partners can increase customer engagement, retention and health outcomes with custom AI health solutions.

Competitive sports are also a target market for Onvy’s capabilities, where the platform can help athletes maintain peak performance, optimal recovery and mental fitness.

“AI is revolutionizing healthcare, and Onvy is at the forefront of this transformation with its cutting-edge approach to real-time health intelligence,” Voloridge Health co-founder David Vogel said. “By seamlessly bridging the gap between raw health data and real-world action, Onvy is shaping the future of precision health, setting a new benchmark for proactive, personalized health coaching. Their ability to turn complex biometric and behavioral data into meaningful, actionable insights enhances both individual well-being and corporate health strategies, delivering measurable outcomes for businesses and consumers alike. We are excited to support their journey as they scale.”

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Few executives have more high-level experience in the supplement industry than Thorne CEO Colin Watts, who has been involved in health and wellness for well over two decades now.

The former CEO of The Vitamin Shoppe, chief innovation officer at Walgreens and president of WeightWatchers Health Solutions, Watts joined Thorne shortly after the wellness and supplement company was acquired by L Catterton in a blockbuster $680 million deal back in October 2023.

That deal, which saw Thorne go private, signaled a new chapter for the company as it looks to make a bigger push into the direct-to-consumer supplement market by providing science-backed products and personalization tools including at-home diagnostic tests, online health quizzes and AI-powered recommendations. 

Watts sat down with Athletech News to discuss how Thorne is working to make supplementation easier and more effective for consumers through personalization, and share his thoughts on the evolution of the supplement industry over the past two-plus decades.

The following conversation has been lightly edited for clarity and length.

Athletech News: You’ve led some of the biggest brands in health and wellness. Why did you decide to join Thorne as CEO in 2023? 

Colin Watts: I got a call from L Catterton when they acquired Thorne to see if I’d be interested in joining the leadership team and eventually coming in as CEO. It didn’t take much of a pitch, honestly. Thorne has a 40-year heritage in the professional channel – in order to service that market, one of the requirements is that your quality has to be pretty unassailable. We’re vertically integrated, so we make (almost) all of our own products in our amazing facility right outside of Charleston, South Carolina.

I also love the innovation profile of the company. What impressed me about Thorne was they weren’t doing the fly-by-night innovation. The supplement industry has a lot of interesting but somewhat superficial innovations that they make a big deal about. Thorne has always been very thorough in its innovation. We were very early into the healthy-aging space, for example. We continue to push in terms of where we’re going with innovation. 

And when I got a chance to meet our people, I saw that the culture is just unbelievable. This is the best company I’ve ever gotten a chance to work for – and I’m not just saying that. 

ATN: When you joined, Thorne, was fresh off a $680 million acquisition. What have your early priorities been as CEO?

CW: My first priority was to take a hard look at how the company was growing and determine where we could prioritize. For decades, Thorne had been a professional-focused company. About seven years ago, we started to pivot more direct-to-consumer, while still continuing in the professional space. As good as Thorne is right now and as big as we become, the reality is that our visibility and accessibility are still fairly low in the category. There’s a lot of headroom, even if you’re a premium supplement brand, to grow that awareness and make sure that more and more people hear the story of Thorne. 

Our second big priority is innovation. In 2025, you’re going to see one of the biggest years of innovation we’ve had in probably 20 years. One of the big areas we’re working on right now is personalization. I think we’re on the cusp of some breakthroughs in personalization, both at Thorne and as an industry.  

ATN: What’s Thorne planning on the personalization front? 

CW: This industry’s been plagued with people over-promising personalization; I’ve watched it for the last 15 years. At the end of the day, if I’m not making changes to my supplement regimen – or my lifestyle overall– then it’s not really personalized. 

At Thorne, we’re taking advantage of advances that are going on right now in AI, along with our participation in the diagnostic, at-home test kit area. We’re also taking advantage of the fact that we’re a leader in the science and professional side, but also master storytellers and very good marketers, to create an experience on the front end of personalization that hopefully will feel as good as the best conversation you could ever have with an expert in the area of supplementation and wellness. We’re going to create something that I believe isn’t going to feel like shopping anymore; it’s going to feel a lot more like asking for help. 

ATN: How has the supplement industry evolved over the last several years?

CW: Today’s consumer, at any age, is no longer thinking about supplements purely from a prevention standpoint. Prevention is really important, don’t get me wrong, but today’s consumer doesn’t want to wait 15 years to see the benefits of supplementation. Frankly, they shouldn’t wait that long.

Gen Zs and Millennials are actually spending more out of pocket for this market than Boomers are, so they’re setting the pace. What we’re seeing is they want to think about supplements – and they want to think about Thorne – as a performance brand. Similar to getting on a treadmill seeing and their (metrics) improving, that same generation is saying, “When I use whey protein, or when I use Catalyte, I want to understand, How is it going to help me perform? How is it going to help me today and tomorrow?”

ATN: The supplement industry is highly crowded, and there’s some consumer distrust. How is Thorne working to separate itself from the crowd?

CW: A long time ago in my career, I got a chance to work with (author and marketing expert) Faith Popcorn. She had this concept that she called a “lighthouse brand.” What she meant is that certain brands in certain industries break out from the pack. If you think about personal computing, Apple is a lighthouse brand. And whether you like Apple or you don’t like Apple, you can appreciate the fact that Apple changed the way that everybody did personal computing and now mobile phones as well. 

I think Thorne has a real opportunity to become a lighthouse brand in this market, because of the quality of our products, the science we put behind our products and our approach in bridging the professional and consumer markets. 

ATN: What’s your vision for the future of Thorne – and the supplement industry in general?

CW: I think we’re coming into a time when supplements will become part of the regular regimen. Consumers taking control of their health: people aren’t just waiting until they get sick, then going to the doctor and saying, “Please treat me.” They’re saying at an earlier age, “I want to perform at my best and I want to stay healthy for the longest I can.”

I’d like to believe Thorne has the opportunity to be a go-to brand. We’re not going to be here one day and gone tomorrow. That said, we also like to think of ourselves as a bit of the maverick of the industry that is constantly innovating and pushing. So if we were having this conversation five years from now, I’d like to be able to point to several points where we as a company have set a new paradigm for wellness and supplementation. 

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New research published this month in Nature Medicine suggests that a range of environmental factors have a greater influence than genetics when it comes to aging well and premature mortality.

Led by researchers from Oxford Population Health, the study analyzed data from nearly 500,000 individuals in the U.K. Biobank to examine the impact of 164 environmental factors and genetic risk scores for 22 major diseases on aging, age-related diseases and premature death.

“We mapped all of the environmental exposures (the “exposome”) influencing mortality and biological aging, and then compared the influence of the exposome vs. genetics in explaining aging and disease,” Dr. M. Austin Argentieri, lead author of the study at Oxford Population Health and Research Fellow at Massachusetts General Hospital, explained in a LinkedIn post. “While genetics certainly play a role, our study highlights that modifiable environmental factors explain far more of the variation in premature mortality than genes do.”

Argentieri then dove into the study’s key findings, such as that the exposome explains nearly 10x more variation in mortality risk than genetic predisposition and that smoking, socioeconomic factors, living conditions, physical activity, sleep, early life factors and psychological well-being were “among the strongest associations with mortality risk and biological aging.”

Of the 25 independent environmental factors identified, smoking, socioeconomic status, physical activity and living conditions had the most significant impact on mortality and biological aging. Smoking was linked to 21 diseases, while socioeconomic factors—such as household income, homeownership, and employment status—were associated with 19 diseases. Physical activity, meanwhile, was connected to 17 diseases.

The study also found that cancers like breast and prostate (as well as dementia) are more genetically driven, while heart, lung and liver diseases are more environmentally driven. 

Argentieri also noted that the association of early life factors—such as childhood body weight at ten years old and maternal smoking around birth—with mortality and biological aging measured 30-80 years later was “striking.”

Encouragingly, 23 of the factors identified are modifiable, according to the findings.

“This work underscores the urgent need for public health interventions that address the exposome—we show that tackling modifiable exposures and environmental risks could be one of our most powerful levers for longevity and healthspan,” Argentieri added.

And in an ever-changing environment, Professor Cornelia van Duijn, St. Cross Professor of Epidemiology at Oxford Population Health and senior author of the paper, says it’s critical that researchers continue to use all resources available to understand the impact of the environment over time.

“There are a lot of questions still to be answered related to diet, lifestyle and exposure to new pathogens (such as bird flu and COVID-19) and chemicals (think of pesticides and plastics), and the impact of environmental and genetic factors in different populations,” van Duijn said.

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Technogym founder and CEO Nerio Alessandri has unveiled a new chapter for the wellness industry with the launch of Healthness, a vision of preventative medicine that enhances physical performance in the short term and ensures healthy longevity in the long term.

The premium fitness equipment company announced at the 25th Wellness Congress, an event that included 2,000 individuals from 100 countries.

The ability to predict disease before it occurs and intervene with prescriptive programs powered by data and AI is at the core of Healthness, which draws from the extensive data Technogym has amassed over several decades through its ecosystem. Healthness will be available via Technogym Checkup, an assessment station that creates precision training programs, as well as its AI-based Biostrength and Biocardio products.

As noted in a narrated video clip from Technogym, “Science shows that lifestyle impacts up to 80% of health, while genetics only account for 20%. Preventing disease will be the greatest revolution of our time, from treating the sick to treating the healthy to prevent them from getting sick later. In 40 years of innovation, from biomechanics to digital technology to AI, Technogym has created a unique AI-driven ecosystem to prescribe precision training with a personalized pathology and lifestyle. Today, Technogym is a life science company ready for a bold step forward.”

The premium wellness company has grown to serve 25 million users and says its latest data-driven initiative not only helps users quickly improve their health and lifespan but also provides an opportunity for medical professionals, personal trainers, and organizations in fitness, sports, hospitality, and corporate sectors to enhance their offerings with a highly personalized approach.

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Prenuvo, the full-body MRI company, has announced that it achieved $100 million in revenue last year and secured $120 million in funding to expand its AI-powered early detection technology further. The investment round was led by Forerunner Ventures, Left Lane Capital, and Felicis, the same backers behind Oura Health.

With newly secured FDA clearance, Prenuvo is launching a new body composition analysis this spring, alongside expanded brain and metabolic health assessments.

“Prenuvo is leading a movement to make proactive healthcare accessible and transformative for everyone,” said CEO Andrew Lacy. “We’re introducing a new approach to early detection that empowers individuals to take control of their health before symptoms emerge. This isn’t just about healthcare; it’s about reimagining how we approach health, using cutting-edge technology and world-class expertise to prevent disease and help people live longer, healthier lives.”

Prenuvo’s newly FDA-cleared AI-powered body composition analysis provides a non-invasive breakdown of visceral fat, subcutaneous fat, liver fat, muscle volumes, and key abdominal organs. The company is also introducing a next-generation brain health scan, offering critical data on cognitive function and early indicators of neurodegenerative diseases. Prenuvo is launching a comprehensive blood biomarker assessment, providing insights into metabolic, cardiovascular, hormonal, and immune health. These capabilities will first be available through Prenuvo Enhanced, a bundled offering launching in Silicon Valley, Los Angeles, and New York, with additional locations rolling out in the spring.

Prenuvo has surpassed 110,000 members and uncovered over 1.4 million personalized health insights. The company is scaling with 15 new clinics, including its first international locations in Europe and Australia.

“With only 2.5% of healthcare spending focused on preventative medicine, the US system waits for people to become sick before intervening,” said Brian O’Malley of Forerunner Ventures. “Consumers have grown tired of this and are responding with their own wallets. Prenuvo is the preeminent solution for a comprehensive understanding of one’s health, giving today’s patients unprecedented levels of knowledge to not just understand but proactively intervene in the challenges that arise as we all age. Longevity is the new luxury, and Prenuvo is democratizing access so that more can benefit from this.”

The post Prenuvo Secures $120M to Expand AI-Powered Technology & FDA-Cleared Health Assessments appeared first on Athletech News.

Pause, a fast-growing wellness and recovery franchise, has partnered with Lifeforce, a longevity medicine program, to launch an integrated longevity-wellness offering. The program leverages blood biomarker results to recommend Pause treatments such as cryotherapy, infrared therapy, contrast therapy, LED light therapy and IV drips.

The collaboration launches at six California locations this month before rolling out nationwide to more than 100 Pause studios by the end of 2026.

“Every year, people spend more and more on taking control of their health, and they’re getting tired of a “spray and pray” approach to that investment,” Lifeforce CEO Dugal Bain-Kim. “As their longevity partner, we’re giving them the insights and the expertise to get the biggest bang for their buck. We looked at lots of players in the recovery space and it was clear that Pause is the gold standard in terms of delivering a premium experience but doing that with a commitment to offering science-backed modalities that actually work.”

Starting this year, members will also be able to have their regular blood draws at Pause studios and receive perks.

“By combining transformational mind/body wellness experiences with Lifeforce’s cutting-edge longevity medicine capabilities, we have created an incredible value proposition for the consumer,” Pause CEO John Klein said. “This is the first partnership of its kind that combines best-in-class longevity telemedicine services with cutting-edge recovery services offered at our studios as a one-stop solution to optimize our members’ health and well-being in a convenient and accessible fashion.”

The concept of prescriptive wellness is taking several forms as longevity is one of 2025’s hottest trends. In addition to Pause, longevity startup Hundred Health, which has been in stealth mode, is gearing up to launch next month. There is also a crossover into wellness tourism, as seen with Canyon Ranch’s new longevity retreat in Tucson and even residential real estate, where motivational speaker Tony Robbins lays the groundwork for The Estate, a high-end hospitality residential ecosystem centered on AI, preventative medicine and longevity. Global hotelier Sam Nazarian, musician Marc Anthony and international strategist Richard Attias are also part of the project.

Last month, athlete-focused healthcare platform Eternal, founded by Alex Mather, The Athletic co-founder and former Strava product lead, secured $13.25 million in a seed round for upcoming clinics in San Francisco and New York City. Slated to open this spring, Eternal clinics will offer bloodwork, Dexa scans and performance testing.

In a post on Medium, early-stage venture capital firm Courtside Ventures, which invested in Eternal’s round, outlined its reasons for backing the longevity concept—emphasizing that it’s less about living forever and more about living well.

“It’s become clear to us at Courtside that while preventative health is the future, functioning health that lets consumers do what they love longer is what is most important,” the team wrote. “In a recent Consumer Survey that asked whether people would rather live 25% healthier or 25% longer, a clear majority across every generation indicated they’d rather live healthier. Within sports, athletes spend thousands of hours in their first couple decades of life dedicated to their craft in hopes of competing at a high level. While nothing (yet) can truly turn back the clock, we believe that athletes can and should be able to enjoy and compete in sport into their marginal decades as a way to truly live fully fulfilled lives.”

The post Pause & Lifeforce Launch Integrated Longevity Program appeared first on Athletech News.

AgelessRx, a telehealth platform specializing in longevity, is launching a needle-free alternative for weight loss medication users with oral sublingual drops.

While the appeal of drops may be appealing to consumers who are squeamish about injectables, oral sublingual drops have another perk: their ability to bypass the digestive system, offering more efficient and faster delivery of the medication compared to traditional oral forms, such as digestible tablets, according to AgelessRx.

“Our mission is to make longevity accessible for all, and GLP-1s are a core piece of that puzzle,” said Stefanie Morgan, vice president of applied sciences at AgelessRx. “The impact of these medications is proving to go beyond traditional uses to significantly improve key health metrics – from metabolic health to glucose regulation, liver function34, heart health and even sleep56 – that could be foundational to a long, healthy life and a key driver in longevity.”

The drops come in both Tirzepatide and semaglutide forms.

Noom and Found have also recently introduced need-free weight loss medication options for their customers. Found has added oral dissolving tablets, and Noom announced it would add oral medications at a $29 entry price for those with a lower BMI than needed to qualify for GLP-1s and those tapering off the weight loss medications. Last spring, Henry Meds added dissolvable tablets to its offerings.

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Regenerative wellness clinic NexGen Health is introducing Niagen Plus IV Therapy, a treatment the Silicon Valley wellness center says supports anti-aging and enhances cellular health.

The IV therapy features nicotinamide riboside (NR), a precursor to NAD+ (nicotinamide adenine dinucleotide), a coenzyme found in all living cells. NAD+ has become a buzzword in the biohacking and wellness space, with proponents suggesting it can help slow the aging process. Sportscaster Erin Andrews is also a fan of NAD+, telling Athletech News recently that she’s on a “whole NAD journey.”

“I’ve been doing that for the last six months,” she shared last month. “I know a lot of the athletes do it as well for inflammation; they do it for the immune system, they do it for cellular health.”

NexGen Health notes that NAD+ levels naturally decline with age, which they say can contribute to fatigue, cognitive decline and other age-related issues. Niagen Plus IV Therapy is designed to replenish NAD+ by delivering NR directly into the bloodstream, bypassing the digestive system for maximum efficacy, according to the clinic.

“Our Niagen Plus IV Therapy is a game-changer for patients seeking to improve energy levels, optimize cognitive function and support overall longevity,” NexGen Health director Ilbra Petros said.”This treatment is perfect for anyone looking to combat the cellular effects of aging and enhance their vitality.” 

The San Jose wellness center also accepts HSA and FSA payments for several of its other services, including peptide therapy, hormone optimization, regenerative medicine, non-invasive aesthetic procedures and medically supervised weight management programs.

For those outside of San Jose, NexGen Health provides a concierge service to book a trip to the center and enjoy a “wellness-cation.” A patient care coordinator assists guests with air travel arrangements, accommodations and transportation. Guests can expect personalized meal plans, nutritious snacks and healthy juices and are encouraged to take advantage of nearby Pilates and yoga studios, locally-sourced restaurants and outdoor activities.

The post Silicon Valley’s NexGen Health Adds Restorative NAD+ IV Therapy appeared first on Athletech News.

SkySlope founder and entrepreneur Tyler Smith is officially pivoting from the real estate management software industry to the wellness and longevity space with Hundred Health, a startup that has been in stealth mode.

Smith is certainly no stranger to the sector, having invested in several longevity and wellness companies, including Function Health, Nucleus Genomics, Devoted Health and TruMe Labs. But behind the scenes, he has been quietly crafting a comprehensive health and longevity platform that promises to be a game-changer: accessible, hyper-personalized and affordable.

While details remain limited ahead of Hundred Health‘s full rollout in March, the startup reflects Smith’s firsthand health experience and his relentless pursuit of data and in improving inefficient systems.

Smith believes the company’s name reflects a “digestible number” for people striving toward better health—perhaps even surpassing 100—a stark contrast to biohacker Bryan Johnson’s ‘Don’t Die’ mantra. Securing the ‘Hundred’ trademark wasn’t easy—Smith says he flew across the world to get it.

As Skyslope’s chief, Smith was immersed in documents, numbers and financials, yet he still prioritized exercise and healthy eating. After scaling the company and selling a majority stake to Fidelity, he remained as CEO and board chair—until a wake-up call set him on a new path.

“At the time, Fidelity had a lot of interesting incentives for their executives,” Smith explains. “I was turning 39, and my wife and I were having our first child a little bit later in life. I began thinking about life a little differently, like, how old is my child when they’re driving? And how old is my daughter going to be when she’s graduating? I wanted to get into health and wanted to get in the best shape of my life.”

Smith then took a biological age test, somewhat confident that his active lifestyle and ideal weight would have proven beneficial in his results, but the test revealed he was biologically 47 years old, eight years older than his chronological age. 

The results caught him off guard—he felt good and thought he looked healthy. But as many entrepreneurs are, Smith is a high-achiever—and saw the results as a challenge. 

The type of person I am—when I see an opportunity to do something, I go full-on, 110%. So I hired some of the best longevity specialists and celebrity doctors, put them around me, and said, ‘What can I do?’ And we ran full diagnostics—from blood biomarkers to different wearables, to genetics, to full-body MRIs. I mean, I went through every single thing,” he says.

After a year—and thousands of dollars invested in his health—Smith says he reversed his biological age to the 30–31 range and felt like a whole new person. His transformation soon inspired others who wanted to turn back the clock and also feel at the top of their game.

The problem was the cost barrier.

Still, Smith recognized the value of having a deep understanding of the body, and with Hundred Health, he’s aiming to make those insights not only accessible but also easy to understand.

“I had more data on my businesses, I have more data, arguably, on my car than I do in my old body,” he says. “That was kind of like a big wake-up call. So that’s what we’re bringing together. We want to bring bio-data, wearables and integrations with a lot of comprehensive blood panels as well as genes, and we’re really tailoring something really unique to that individual at scale. The best part about it is like we’re doing this at a really affordable price, less than $1.50 a day.”

From what Smith could disclose, Hundred Health will include a form of testing and then generate tailored protocols for each individual, spanning pillars like nutrition, diet, lifestyle, exercise and more. The experience will live on both mobile and the web and will feature additional add-ons that will likely be shared in March ahead of Hundred Health’s official launch, he added.

“What we’ve built against some of the best out there is really eye-opening to what you could do when you have a lot of data on a person and what you’re able to really give them, and then make it wildly digestible, “he says. “And I think we’ve solved that.”.

As a successful entrepreneur, Smith believes the timing couldn’t be better. As the fitness and wellness industry is witnessing, there’s strong demand and energy from both consumers and investors for more accessible and personalized solutions, especially as frustrations mount towards traditional healthcare. Additionally, many are overwhelmed by information overload.

“I think COVID really changed people’s perception,” Smith suggests. “If you go [back] to the early COVID days, it was, ‘I have to do vaccines. I have to do what I’m told to do,’ to—fast forward to the wildest time right now—when you see what’s happening with the election and Robert F. Kennedy Jr. and this huge movement of people [feeling], ‘I want to know what is going on with my body. I don’t want someone to tell me.’ And I think you’re seeing this across the board.”

The startup says its cohort consists of individuals in the 30–50 age range—those who want to understand what’s happening in their bodies on a personal level while also receiving support to achieve their “GHOAT,” as Smith puts it.

“People think of ‘GOAT’ like LeBron James or Serena Williams. To us, GOAT is G, H, O, A, T: Greatest Health of All Time,” Smith says.

Based on Hundred Health’s preliminary assessment, interested consumers are showing a 60% female and 40% male split. Smith says female members can expect a level of specialization tailored to their needs.

There’s also a corporate wellness play in development for Hundred Health, which Smith alluded to.

“We have a direct consumer play that’s quite compelling…and then you can imagine something like this at the price point that we’re at – it’s really attractive for businesses,” he says. “As you know, healthy employees are happy employees and healthy and happy employees are more productive.”

Due to the size of its waitlist, Smith says Hundred Health’s first cohort will launch toward the end of March, with new consumers gradually added each month.

“We’ve got a lot of people who I know this would serve,” he says. “And we’ve brought a price point that I think is going to be transformative for people.”

As for embarking on an entirely new direction in his career, Smith is keeping ties at Skyslope as executive chair, CEO, and his enthusiasm is apparent for the upcoming transition.

“I’m massive on change and transition. I think any entrepreneur, you’re changing all the time, whether that’s competitors, team members, employees, culture – you’re constantly changing,” Smith says. “I love change. Our bodies change daily; some of us just don’t know it, right? I’ve been very inspired again. It’s a mission-driven business for me and the team as well. We’ve got a really cool team, and everyone’s hungry. We are tenacious and we really want to help folks achieve their ‘GHOAT’, and we’re going to really push hard to make sure that’s achievable.”

The post Hundred Health, a Stealth Longevity Startup, Gears for Launch appeared first on Athletech News.

Healthspan and longevity membership program Preamble — a Medicine 3.0 care model founded by Dr. Jesse Greer, a former Green Beret, Special Forces physician and flight surgeon — has partnered with The Village Health Clubs and Spas to launch a four-month personal vitality program featuring customized fitness and nutrition plans.

Dubbed ‘The Village Vitality Program Powered by Preamble,’ members can undergo comprehensive baseline testing covering metabolic function, body composition, strength, inflammation, cholesterol, hormones and more and a customized lifestyle program designed by a team of experts. Weekly personal training sessions are also part of the program at The Village, as well as monthly nutrition consultations, check-ins with a personal performance coach, monthly body composition scans featuring InBody and educational modules on health and wellness. 

The program is offered at all four of The Village Health Clubs and Spas locations in Arizona and requires an investment of $4,150. However, the program is eligible for Health Savings Accounts (HSA) and Flexible Spending Accounts (FSA) for the $2,000 medical portion. The addition of Premable ties in nicely with The Village’s existing offerings, which include group fitness, personal training, pickleball, tennis, basketball, golf, fencing, racquetball, squash, a spa and salon.

“The Scottsdale community is full of individuals dedicated to achieving a healthier, longer life,” Dr. Greer said. “Preamble supports this goal with a health approach centered on longevity-focused medicine that emphasizes preventative care, performance optimization and comprehensive health analysis rather than solely focusing on treatment. We’re thrilled to collaborate with The Village, a cornerstone of health and wellness in the community, to bring this innovative program to their fitness-forward clientele.”

After the four-month program, members undergo final testing and receive personalized recommendations to support their long-term health.

A New Approach

Preamble’s vision for health and wellness comes amid growing interest in longevity, frequent dissatisfaction with traditional healthcare and its barriers and the overwhelming flood of information.

“My time as a Special Forces physician, both in the field and back home, shaped my approach to healthcare,” Dr. Greer told Athletech News last fall. “I learned that early detection and proactive intervention are as vital in medicine as they are in combat, preventing problems before they become life-threatening. After working in traditional medical settings, I saw how reactive American healthcare often left patients vulnerable, addressing issues only after they’d advanced too far. This realization fueled my passion for a preventive model that prioritizes long-term wellness.”

Making Preamble accessible in terms of pricing was fundamental, Dr. Greer adds.

“The approach we’ve developed is incredibly effective, but traditionally, it’s been out of reach for most people,” he said. “The technology to deliver personalized, high-quality care is here now and only getting better. By designing flexible, scalable programs, we can finally bring these transformative health strategies to a broader audience. If we want to see a healthier nation, this type of care needs to be available to everyone who truly wants it. It’s not just about offering elite care; it’s about democratizing wellness so that anyone committed to improving their health has the opportunity to do so.”

He also sees a shift in the approach to long-term health.

“More and more people are waking up to the reality that the overall health of the U.S. population is on a decline, and the answers aren’t found in a pill or quick fix,” he said. “They’re realizing that staying healthy requires a proactive approach—one that focuses on preventing problems before they start.”

Yet even with the wealth of health data now available—such as full-body MRIs, direct-to-consumer blood tests, and continuous glucose monitors—guidance remains key, Dr. Greer says.

“Most people need help making sense of it all and turning that information into practical, real-life actions that improve their health,” he said. “Add to that a cultural shift where the media is buzzing with talk about longevity and wellness. This is helping people visualize the healthy, vibrant life they want to live for decades to come. It’s no longer just about avoiding sickness—it’s about being the best version of yourself for the long haul.”

Preamble Looks Ahead

Preamble offers a hybrid mode that pairs remote care and in-person interactions and will establish Preamble clinics in cities across the U.S. over the next few years, which will serve as hubs for advanced testing, such as Dexa scans and VO2 max testing. The centers will build on Preamble’s first in-person clinic, which opened in Scottsdale, Arizona, in 2023.

“These regional centers will also play a crucial role in supporting local physicians and lifestyle partners, such as performance coaches,” Dr. Greer says. “Ultimately, our goal is to create a network of regional hubs that bring advanced, personalized care to communities nationwide, supporting a healthier future for everyone.”

Three plans are currently offered:

A Preamble Physical+, $1,999, is eligible for HSA/FSA payment and includes a baseline health assessment with biomarker blood testing, resting metabolic and strength testing and an In-Body scan. The results are compiled in a Health Intelligence Report and there is a 45-minute review with a Preamble physician assistant. There is also a 60-minute strategy session with a Preamble MD to go over a personalized lifestyle action plan.

A Preamble Pro membership plan, $6,500 and also eligible for HSA/FSA payment, is designed for those who need additional guidance and advanced treatment protocols and includes quarterly re-evaluations, access to prescription services, monthly accountability check-ins and in-clinic advanced metabolic and exercise testing with unlimited standard lab work and In-Body scans.

Medicine 3.0, $399, for those who want to ensure they are on the right track and includes core metrics and a fitness assessment, with a 90-minute session that reviews exercise and resting rates, VO2 max, custom heart rate training zones and optimal fat-burning zone. A personalized report is then reviewed with a Preamble performance coach.

The post Preamble & Village Health Clubs & Spas Launch Vitality Program appeared first on Athletech News.

Longevity. Holistic wellness. Anti-aging. Metabolic health. Gut health. Femtech. Once niche buzzwords reserved for the wellness-savvy, these terms have entered mainstream conversations, sparking discussions among friends and peers.

As many focus on foundational steps to take control of their health, others are diving deeper—embracing cutting-edge technologies and tools that aim to enhance vitality and, hopefully, extend their lifespan.

It’s an exciting space, but it can be overwhelming—especially when trying to distinguish fleeting fads from lasting trends poised to shape the future of the wellness industry. 

With a new year underway, Athletech News connected with leaders across various health sectors to explore the trends and technologies they believe will define the wellness landscape in 2025 and beyond.

AgelessRx Co-Founder Reflects on Potential of GLP-1 Microdosing and Rapamycin

Dr. Sajad Zalzala, chief medical officer and co-founder of AgelessRx, expects Geroprotective therapies (interventions tackling aging) to pick up speed in 2025, building on the momentum of research released in recent years.

His telehealth company, centered on longevity, has captured the interest of consumers averaging 50 years old and high-performers who need to squeeze the most out of every breath. 

“I suspect we will see a wider and broader interest in Rapamycin as it gets studied for chronic fatigue syndrome, long COVID, female fertility, oral health, chronic pain and more,” Dr. Zalzala adds, referencing the FDA-approved drug.

He also projects that NAD+ will continue to experience strong interest due to its versatile benefits across several health domains and its pop culture ties, catapulted in part by Hailey Bieber and Kendall Jenner, NAD+ fans. 

At the same time, Dr. Zalzala also expects GLP-1 medications to gain interest for its benefits beyond weight loss, appealing as a solution to those struggling with inflammation and addiction. He also predicts an emphasis on GLP-1 microdosing for cost effectiveness, longevity benefits and tolerance in the near future. Dr. Zalzala isn’t alone; functional medicine expert Dr. Frank Lipman also sees the potential of GLP-1 microdosing. 

In addition to a focus on mental wellness and cognitive health, the AgelessRx co-founder also projects an increase in personalized wellness tools.

“As people are becoming more interested in the inner workings of their bodies, we’re seeing more demand for micronutrient and microbiome testing as well as using wearables to guide therapies and outcomes,” Dr. Zalzala says.

23andMe’s Dr. Abul-Husn on the End of One-Size-Fits-All Solutions

23andMe’s vice president of genomic health, Dr. Noura Abul-Husn, shares Dr. Zalzala’s prediction on personalized wellness. 

“Personalized wellness, driven by the unique intersection of genetic insights and blood/biological age data, will have a lasting impact into 2025 and beyond,” Dr. Abul-Husn says. “People are becoming more interested in tailoring their fitness and health routines to their unique genetic makeup, recognizing that a one-size-fits-all approach doesn’t work for everyone.”

Similarly, Dr. Abul-Husn believes the emphasis on mental wellness also has staying power — with mindfulness, meditation, breathwork and stress management becoming an essential part of a comprehensive health stack. 

“Focusing on mental health and implementing practices like meditation and mindfulness can alleviate stress and anxiety, factors that can contribute to neurological diseases like Alzheimer’s and Parkinson’s,” Dr. Abul-Husn says. “As we continue to understand even more about the connection between mental and physical health, these holistic approaches will only become more prevalent.”

This year, we are also likely to see generalized health recommendations like recommended daily allowances and general nutritional guidelines fade, predicts Dr. Abul-Husn.

“Advances in personalized wellness and nutrition are showing that factors like age, weight, daily activities and even genetics influence nutritional requirements,” she says. “Genomics and other technologies are helping provide a clearer picture of one’s specific health needs. This shift supports an approach where nutrition and health recommendations are tailored to each person’s lifestyle and genetic makeup or biology, offering more precise guidance that can improve health and longevity.”

NextSense’s Caitlin Shure Excited for Closed-loop Wearables, Rise of Femtech

NextSense head of product and content Caitlin Shure, PhD, is eyeing several trends for 2025, related to wearables, femtech and women’s health.

While sporting a wearable on the wrist has become commonplace, Dr. Shure points out that there is a desire for wearable devices to be discreet, comfortable and even stylish.

“Products like the Oura Ring have become popular due to their sleek design and comfort, and future wearables will likely emphasize these aspects to appeal to a broader audience,” Dr. Shure says. “Current wearable form factors, such as bulky EEG headbands, remain less socially acceptable, limiting mainstream adoption. With the next generation of wearables, companies are striving to integrate advanced technologies like EEG into more subtle, fashionable designs—making health tracking not only functional but also aesthetically appealing for everyday wear.”

She also hints at an exciting new development in the wearable tech space: closed-loop wearables that create feedback loops to make adjustments for optimal health, such as automatically adjusting settings for relaxation or signaling users when their stress levels are too high. Advancements like these are what position wearables as an active partner in health management rather than a simply passive tracker, she says. 

Tech company NextSense is leading the way in the space, having created brain-responsive earbuds that support sleep and energy enhancement.

Notably, Dr. Shure points out the rising femtech industry — an exciting and important space that is focused on products addressing women’s health needs – is poised to grow rapidly in 2025 and beyond.

“With ongoing advancements in menstrual tracking, hormonal health, reproductive support and even menopause management, femtech is gaining traction as a valuable sector within wellness,” Dr. Shure says. “From apps to wearable devices tailored to women’s unique health needs, femtech innovations are becoming a crucial part of both preventative and personalized health. This continued focus on women’s health reflects a broader trend toward inclusive wellness and the development of tech that acknowledges different health needs across demographics.”

Dr. Davis Champions Heart Health, Metabolic Disease Solutions 

Humann chief cardiologist Dr. Chris Davis, FACC, offers a compelling prediction for 2025 that is right in his wheelhouse: the endothelial glycocalyx.

For laypersons who are unfamiliar with this gel-like layer of glycoproteins, Dr. Davis assures that we will soon hear more about its role in maintaining healthy blood vessels and preventing heart disease. 

“Many people don’t know that the glycocalyx is a layer that lines the inside of your arteries, shielding them from damage and helping keep blood cells, white blood cells and cholesterol molecules flowing smoothly through your arteries,” Dr. Davis says. “A healthy glycocalyx helps ensure that your arteries produce nitric oxide, a vital molecule for maintaining healthy blood flow and blood pressure.” 

Humann, a heart health supplement company, welcomed the triple board certified physician to their team last summer.

Dr. Davis also points to the increased interest in cardiometabolic health, which has become a more common focus as more individuals discover the connection between cardiovascular health and properly functioning metabolic systems. This attention will likely lead to awareness of new remedies. 

“For example, studies show the benefits of berberine as a tool to support blood sugar and blood pressure management, insulin resistance and cholesterol levels, and we may see a rise in the popularity for solutions like these to help mitigate metabolic disease,” Dr. Davis says.

Dr. Bulsiewicz Explores Gut-Immune Connection, Microbiom Nutrition 

While Dr. Davis has the heart covered, Dr. Will Bulsiewicz, a gastroenterologist and founder of gut health supplement company 38Tera, noted the growing awareness of gut-immune connection. 

“2025 will be the year people prioritize their gut health not just for digestion, but for whole-body immunity,” he says. “The gut and the immune system are inseparable, and the best way for us to reduce inflammation is by healing the gut. You will hear more about this in the coming year.”

The New York Times bestselling author of “Fiber Fueled” also points out that there’s a new generation of gut health supplements in the pipeline for this year. 

“I’m excited to play a central role in making this happen,” Dr. Bulsiewicz says, adding that he launched 38Tera last year. “Our flagship product – DMN, or Daily Microbiome Nutrition – is a powerful overhaul of Grandma’s orange drink using cutting edge science and premium ingredients. It helps you feed your microbes daily in a way that’s easy, delicious and effective. In 2025, 38Tera will expand its range with evidence-based solutions to common gut issues.”

Much like the other experts in their respective fields, he emphasizes the role of personalization when it comes to the future of the wellness industry.

“This year, personalized gut health solutions will dominate the wellness space, with microbiome testing and tailored nutrition plans becoming more accessible than ever,” he adds. “This is something I’m personally involved with as the U.S. medical director of ZOE.” 

The post What’s Defining Wellness in 2025? Here’s What 5 Experts Say appeared first on Athletech News.

Springbok Analytics, developers of an FDA-cleared AI tech platform that generates automated muscle health assessments from MRI scans, has closed an oversubscribed $5M Series A funding round. 

The startup is tackling three key areas with its technology, delivering the ultimate trifecta and highlighting the investor enthusiasm surrounding life sciences, elite sports and longevity.

Springbok currently offers three rapid MRI muscle health scan options—lower extremity, core, and full body—with total imaging times ranging from 10 to 35 minutes. After the scan, images are processed by Springbok’s AI-based software and reviewed for quality. A personalized report is then created, featuring 3D muscle visualizations and data, including an analysis of tendons, bones, scar tissue and edema—typically available within 1-2 business days. Springbok recommends an annual scan alongside a traditional physical check-up to provide actionable insights to better manage muscle health, provided there are no underlying conditions, such as an injury.

Elite athletes, on the other hand, may undergo 3-4 scans a year or more, depending on whether they are rehabbing from an injury or recovering post-surgery. Additionally, the insights can help trainers and coaches optimize performance and recovery.

Transition Equity Partners, LLC (TEP), which led the seed round for the muscle health analytics company, once again served as the lead investor. Additional participants in the Series A included the National Basketball Association, Cartan Capital, Boston Global and other strategic investors.

Pat Eilers, managing partner and founder of TEP, emphasized that Springbok’s recent FDA clearance marks a significant achievement, underscoring the value of its technology and “opens up exciting commercial opportunities in healthcare, including visibility to reimbursement.” He added that this advancement holds potential benefits for athletes of all levels, as well as the broader health and wellness of the general public. 

The funding will support Springbok Analytics’ reach and continued innovation, co-founder and chief scientific officer Silvia Blemker said.

“I’m incredibly proud of our progress and excited about the opportunities ahead to advance muscle research, improve patient outcomes and empower human performance,” Blemker added.

Another focus area for Springbok will be clinical trials and research.

“This investment positions Springbok to become the global leader in precision muscle health analytics,” Springbok Analytics CEO and co-founder Scott Magargee said. “We are committed to pioneering advancements that redefine muscle health and enhance human performance.”

Springbok’s funding comes as the importance of strength training becomes a focal point of consumers, considering its numerous health benefits and reduction in cancer-related deaths. It also represents a changing tide in how consumers can approach health and wellness by prioritizing prevention and circumvent the traditional healthcare landscape with supplemental testing. Neko Health, a health tech startup co-founded by Spotify founder Daniel Ek, just secured $260 million for its non-invasive body scan system as it gears up for a U.S. launch. As of now, Neko Health has a waitlist north of 100,000 individuals for its scans, representing the massive interest in new health technology.

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